2008ApJ...676..978B

Hot-core molecules should be detectable in external active galaxies out to high redshift. We present here a detailed study of the chemistry of star-forming regions under physical conditions that differ significantly from those likely to be appropriate in the Milky Way Galaxy. We examine, in particular, the trends in molecular abundances as a function of time with respect to changes in the relevant physical parameters. These parameters include metallicity, dust:gas mass ratio, the H₂ formation rate, relative initial elemental abundances, the cosmic-ray ionization rate, and the temperature of hot cores. These trends indicate how different tracers provide information on the physical conditions and on evolutionary age. We identify hot-core tracers for several observed galaxies that are considered to represent spiral galaxies, active galaxies, low-metallicity galaxies, and high-redshift galaxies. Even in low-metallicity examples, many potential molecular tracers should be present at levels high enough to allow unresolved detection of active galaxies at high redshift containing large numbers of hot cores.